Parameters | Value | Biological significance |
---|---|---|
C A M ∗ | 4 μM | Threshold Mitochondrial Ca2+ |
y ∗ | 0.8 | Secondary process threshold |
\(f_{H_{M}} \) | 1.28 x 10 −6 | Fast buffering constant for protons in mitochondria |
p 1 | 0.022 | Parameter p1 |
p 2 | 0.0001 | Parameter p2 |
p 3 | 0.0231 | Parameter p3 |
p 4 | 0.0001 | Parameter p4 |
a m p τ | 26000 | Amplitude for time constant |
p 6 | 0.001 | Parameter p6 |
\(perm_{l}^{H}\) | 3.0 | PTP Permeability to protons |
p e r m Ca | 0.4 | PTP Permeability to calcium ions |
postptp | 2 | PTP opening indication constant |