Equation | Biological significance |
---|---|
Mitochondrial uniporter equations | |
MWC num =(CAC/6)∗((1+(CAC/6))3) | MWC numerator |
MWC denom =((1+(CAC/6))4)+(50/((1+(CAC/0.38))2.8)) | MWC denominator |
MWC=MWC num /MWC denom | MWC fraction value |
\( V^{D}_{uni} = \left (PSI - 91\right)/13.35 \) | Uniporter potential exponent |
\( J_{uni} = \left (\rho _{uni} * V^{D}_{uni} * \left (MWC - CAM * exp\left (-V^{D}_{uni}\right)\right)/\left (1 - exp\left (-V^{D}_{uni}\right)\right)\right) * \left (1-PTP_{h}\right) \) | Rate of transport through uniporter considering PTP in high conductance state |
Na+/Ca2+ exchanger equations | |
\( V^{D}_{nc} = exp\left (\left (PSI - 91\right)/53.4\right) \) | Na+/Ca2+ exchanger potential generated |
\( J_{nc} = \left (\rho _{nc} * V^{D}_{nc} * \left (1/\left (1 + \left (9.4/30\right)**2\right)\right) * \left (1/\left (1 + \left (0.003 * Dmito/CAM\right)\right)\right)\right) * \left (1-PTP_{h}\right) \) | Rate of Na+/Ca2+ exchange |