Fig. 3From: Composite mathematical modeling of calcium signaling behind neuronal cell death in Alzheimer’s diseaseOverall time-course simulation showing cytosolic (CAC) and mitochondrial (CAM) Ca 2+ ion concentration along with tendency for opening of PTP in high-conductance state (PTPh) over a time of 500ms in the absence of β-amyloid deposition (by setting V1 = 0, V α = 0 and K1 = 0)Back to article page