From: Modeling the therapeutic efficacy of NFκB synthetic decoy oligodeoxynucleotides (ODNs)
Abbreviation | Full name |
---|---|
D B | Bound decoy site |
D U | Unbound decoy site |
A D B | Bound artificial decoy site |
A D U | Unbound decoy site |
ON | Active gene state |
OFF | Inactive gene state |
I n | Nuclear IκBα |
I c | Cytoplasmic IκBα |
N n | Nuclear NFκB |
N c | Cytoplasmic NFκB |
N I n | Nuclear NFκB−IκBα complex |
N I c | Cytoplasmic NFκB−IκBα complex |
N | Total number of NFκB: 105 |
Gene≡ON+OFF | Total number of Genes: 1 |
AD≡AD B +AD U | Total number of artificial Decoys: [0−2×105] |
D≡D B +D U | Total number of natural Decoys: 2×104 |