Fig. 9
From: Robust and efficient parameter estimation in dynamic models of biological systems
Calibration and cross-validation results for the GOsc case study. Left figure shows fits to calibration data, right figure shows agreement of predictions for cross-validation data. The non-regularized and the regularized fits show some differences in the first two oscillations, although at the measurement times the predictions are almost identical. In cross-validation, the non-regularized model shows a heavy overshoot at early times