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Table 2 Posterior probability share of each objective function, listing in descending order of probability

From: Genome-scale metabolic model of Rhodococcus jostii RHA1 (iMT1174) to study the accumulation of storage compounds during nitrogen-limited condition

Objective Functiona

Posterior Probability Share (%)

Maximization of storage and environmental MOMA

76.20

Maximization of storage

21.30

Environmental MOMA

2.37

Flux minimization

6.57 × 10−2

Minimization of ATP production

2.13 × 10−2

Maximization of ATP production

2.13 × 10−2

Minimization of NADH production

2.13 × 10−2

  1. aNote that the experimentally observed NGAM were 23 and 39 mg-CODstorage compounds/(g-CODbiomass·h) on glucose and acetate, respectively. The calculated NGAM values (in mmol/(g-DW·h)) at the measured total storage flux for different objective functions on glucose are as follows: minFluxes: 2.236, maxATP, minATP, minNADH: 1.200, maxStorage: 3.502, and maxStorage+environmental MOMA: 3.44. The calculated NGAM values (in mmol/(g-DW·h)) at the measured total storage flux for different objective functions on acetate are as follows: minFluxes: 3.385, maxATP, minATP, minNADH: 3.409, maxStorage: 4.027, and maxStorage+environmental MOMA: 3.823
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BMC Systems Biology

ISSN: 1752-0509

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