Table 1 Identified network modules

A (yellow)

198

metabolic process; amine metabolic process; negative regulation of peptidase activity; lipid biosynthetic process; oxidoreductase activity; electron carrier activity

Liver weight (-0.91), Triglycerides (-0.90), Atherosclerosis (-0.79), Cholesterol (-0.79)

B (red)

161

cell activation; response to stress; immune system process; inflammatory response; cytokine production

Atherosclerosis (0.80), Cholesterol (0.78), Liver weight (0.75)

C (black)

142

lipid metabolic process; carboxylic acid metabolic process; acyl-CoA metabolic process; thioester metabolic process; oxidation-reduction process

Liver weight (0.88), Cholesterol (0.83)

D (green)

185

aromatic amino acid family catabolic process; cofactor binding; rRNA binding; endopeptidase inhibitor activity

E (royalblue)

51

Cholesterol (-0.82)

F (blue)

369

protein localization; protein transport; generation of precursor metabolites and energy

G (magenta)

125

circadian rhythm

H (purple)

118

regulation of primary metabolic process

I (greenyellow)

112

receptor activity

J (cyan)

83

K (lightyellow)

54

L (darkgreen)

41

M (darkturquoise)

39

electron transport chain

N (orange)

22

hexosaminidase activity