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Table 2 Pegasus predictions on GBM RNA-Seq data

From: Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer

5’ Gene partner

3’ Gene partner

Pegasus driver score

Recurrence

YEATS4

XRCC6BP1

0.9598

1

EIF4H

GTF2I

0.9440

1

ASH1L

C1orf61

0.9256

1

SEC61G

EGFR

0.9234

4

BCAN

NTRK1

0.9182

1

EGFR

VOPP1

0.9130

2

EGFR

SEPT14

0.9042

6

TDRD3

ESD

0.8959

1

TFG

GPR128

0.8880

4

PPP2R2B

CCT3

0.8699

1

TBC1D14

HTRA3

0.8697

1

FGFR3

TACC3

0.8442

3

LANCL2

SEPT14

0.8428

3

  1. Pegasus top driver scores (PDS > 0.8) predicts 46% of known driver gene fusions in GBM data from TCGA cohort. Recurrence is assessed on the basis of gene fusion frequency reported in Frattini et al. and Brennar et al.
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BMC Systems Biology

ISSN: 1752-0509

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