Figure 2
Sensitivity analysis. Heat-map representing the sensitivity correlation S, computed using: A) the normal expression data for the top-correlated mRNA/lncRNA pairs (N = 87398) in the normal dataset. Light vertical stripes point to a little pool of miRNAs that is responsible for the high correlation between all top-correlated mRNA/lncRNA pairs; B) the cancer expression data for the top-correlated mRNA/lncRNA pairs in the normal dataset; C) the cancer expression data for the top-correlated mRNA/lncRNA pairs in the cancer dataset. Rows: top-correlated mRNA/lncRNA pairs; columns: miRNAs. Color key: red to blue scale corresponds to low to high S. Top-correlated mRNA/lncRNA pairs: Pearson correlation values exceeding the 99th percentile of the overall correlation distribution (i.e., r>0.7 in normal and r>0.4 in cancer).