Prediction of protein interaction types based on sequence and network features

BMC Systems Biology

Table 3 Sizes of protein interaction networks in human, yeast, and E. coli.

	Human	Yeast	E. coli	Total
Nodes	9917	5528	2068	17513
Non-redundant interactions	41115	39045	7197	87357
Raw interactions	77742	59336	13068	150146
Yeast two hybrid (MI:0018)	13876	11055	54	24985
Anti-tag coimmunoprecipitation (MI:0007)	1311	10049	0	11360
Pull down (MI:0096)	6651	4024	78	10753
Experimental interaction detection (MI:0045)	8243	23	6	8272
Enzymatic study (MI:0415)	1002	2	4	6491
Inferred by author (MI:0363)	0	388	5898	6286
Anti-bait coimmunoprecipitation (MI:0006)	5984	22	2	6008
Tandem-affinity purification (MI:0676)	317	3631	1112	5060
Others	40358	30142	5914	76414

Non-redundant interactions: each unique combination of interactors A and B is counted as a single interaction, regardless of directionality, experimental system, and data source. Raw interactions: Each unique combination of interactors A and B, experimental system and data source is counted as a single interaction^a. Each interaction detection method is annotated with its Ontology Term (e.g. MI:0018).

ISSN: 1752-0509