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Table 4 Comparison of the functional enrichment of protein complexes identified by LF-PIN and other algorithms (for S.cerevisia e)

From: Identifying protein complexes based on density and modularity in protein-protein interaction network

Algorithms

<E-10

[E-10,E-5]

[E-5, 0.01]

≥0.01 insignificant

<0.01 significant

LF-PIN

63(21.2%)

93(31.3%)

103(34.7%)

38(12.8%)

259(87.2%)

CMC

73(6.5%)

191(16.9%)

292(25.9%)

574(50.8%)

556(49.2%)

Core-Attachment

76(5.6%)

122(9.0%)

287(21.1%)

873(64.3%)

485(35.7%)

CPM

25(12.7%)

49(24.9%)

42(21.3%)

81(41.1%)

116(58.9%)

DPClus

42(3.5%)

155(12.9%)

329(27.4%)

674(56.2%)

526(43.8%)

HC-PIN

40(15.1%)

42(15.9%)

84(31.7%)

99(37.4%)

166(62.6%)

MCL

54(5.8%)

114(12.3%)

239(25.7%)

522(56.2%)

407(43.8%)

NFC

63(21.2%)

81(15.6%)

124(23.9%)

266(51.3%)

259(87.2%)

  1. The table lists the percentages of protein complexes identified by LF-PIN, CMC, Core-Attachment, CPM, DPClus, HC-PIN, MCL and NFC in PPI network of S.cerevisiae whose P-value falls within < E-10, [E-10, E-5], [E-5, 0.01] and ≥0.01.