Table 4 Recon 1 metabolic pathways differentially represented in tumor and normal tissues
From: Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
Pathwaysa | % complete in tumor models | % complete in normal models | Rank sum p-value |
|---|---|---|---|
Folate Metabolism | 50% | 27% | 2.8E-03 |
Eicosanoid Metabolism | 34% | 13% | 6.6E-04 |
Fatty acid activation | 91% | 81% | 1.8E-02 |
Tryptophan metabolism | 17% | 10% | 1.2E-02 |
Transport, Lysosomal | 17% | 11% | 7.8E-03 |
Nucleotides | 69% | 63% | 1.9E-04 |
Aminosugar Metabolism | 56% | 53% | 4.8E-02 |
Transport, Mitochondrial | 25% | 23% | 3.4E-02 |
Sphingolipid Metabolism | 13% | 12% | 3.2E-02 |