Table 1 KARE result: top 5 gene sets with smallest q-value associated with hypertension phenotype from Z-statistic method
From: SNP-PRAGE: SNP-based parametric robust analysis of gene set enrichment
Gene set | No. genes | No. SNPs | p-value | q-value |
|---|---|---|---|---|
ST_JNK_MAPK_PATHWAY | 36 | 2410 | 1.13 × 10-4 | 6.38 × 10-2 |
HSA00563_GLYCOSYLPHOSPHATIDYLINOSITOL_ANCHOR_BIOSYNTHESIS | 18 | 700 | 2.67 × 10-4 | 6.57 × 10-2 |
FASPATHWAY | 28 | 1489 | 8.82 × 10-4 | 1.44 × 10-1 |
HSA05060_PRION_DISEASE | 117 | 762 | 2.42 × 10-3 | 2.53 × 10-1 |
HSA04520_ADHERENS_JUNCTION | 64 | 4150 | 2.58 × 10-3 | 2.53 × 10-1 |