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Table 3 The experimentally validated TFBS that occurred in bi-directional promoters

From: Genome-wide analysis of the transcription factor binding preference of human bi-directional promoters and functional annotation of related gene pairs

TF name

Fold Enrichment

Regulated gene pair

Reference

GABPA

7.069

Gapba/Atp5j

PREPL-C2ORF34

[19]

[29]

E2F1

6.893

TK/KF genes

[10]

NFY

5.255

Mrps 12/Sarsm

PREPL-C2ORF34

Mrps 12/Sars2

[30]

[29]

[31]

SP1

3.398

OSGEP/APEX

Gapba/Atp5j

DEIN/HAND2

HSF-1/Bop1

E14/ATM

[32]

[19]

[8]

[33]

[34]

CCAAT box

2.687

BRCA1/NBR2

GPAT/AIRC

OSGEP/APEX

mOsgep/mApex

[35]

[36]

[37]

[38]

NF1

2.591

Pxmp2/Polel

[39]