Table 3 Estimated parameter values for the different experiments (RKI, NIBSC, mock).
| Â | Virus infection | Mock | |||||
|---|---|---|---|---|---|---|---|
| Â | RKI1 | RKI2 | RKI3 | NIBSC1 | NIBSC2 | Exp. 1 | Exp. 2 |
X uinf (0) | 3.10 | 2.91 | 2.95 | 2.87 | 2.81 | 3.21 | 2.92 |
X det (0) | 0.17 | 0.25 | 0.0 | 0.36 | 0.0 | 0.0 | 0.05 |
X ui (106/mL) | 0.70 | 0.93 | 1.10 | 0.70 | 0.67 | Â | Â |
r lys (1/h) | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 |
r inf (1/h) | 5 | 5 | 5 | 5 | 5 | Â | Â |
r mm /r adp (1/h) | 0.70 | 0.70 | 0.70 | 0.80 | 0.80 | 1.0 | 1.0 |
r det (10-3/h) | 44.1 | 76.3 | 100.5 | 109.6 | 135.2 | 11.8 | 3.0 |
Ï„ inf /Ï„ adp (h) | 6.3 | 6.3 | 6.4 | 5.2 | 5.7 | 4.0 | 10.0 |
Ï„ det (h) | 3.0 | 5.7 | 4.2 | 5.1 | 4.4 | Â | Â |
r Glc,1 | -28.5 | -70.9 | -18.5 | -403.5 | 0.0 | -33.9 | -61.1 |
rGlc,2(fmol/cell/h) | -93.0 | -157.5 | -192.9 | -66.0 | -255.4 | -51.8 | -45.0 |
r Lac,1 | 124.5 | 1.5 | 69.2 | 177.6 | 252.1 | 43.9 | 140.8 |
r Lac,2 | 509.8 | 728.8 | 985.9 | 666.9 | 809.9 | 338.6 | 295.3 |
r Glu,1 | -5.0 | -6.7 | -9.4 | -10.0 | -10.4 | -2.6 | -1.6 |
r Glu,2 | -0.8 | 10.5 | 12.6 | 20.4 | 16.5 | -4.3 | -1.7 |
r Gln,1 | -6.2 | -31.1 | -0.2 | -40.1 | -0.5 | -5.5 | -26.1 |
r Gln,2 | -7.4 | 0.0 | -3.6 | 0.0 | -5.9 | -9.3 | -5.6 |
r NH 4,1 | 7.8 | 5.5 | 2.8 | 3.2 | 2.2 | 20.8 | 16.0 |
r NH 4,2 | 17.4 | 19.7 | 8.0 | 19.7 | 10.5 | 15.5 | 7.8 |
rVP,2(VP/Cell/h) | Â | 27500 | 30800 | 9600 | 9300 | Â | Â |
Glc(0) (mmol/L) | 31.6 | 32.7 | 32.7 | 33.8 | 31.9 | 32.2 | 32.9 |
Lac(0) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glu(0) (μ mol/L) | 298.5 | 195.7 | 315.0 | 175.7 | 362.7 | 298.2 | 157.3 |
Gln(0) | 1.6 | 2.2 | 0.8 | 2.1 | 0.8 | 1.7 | 2.2 |
HA(0) (logHA) | Â | 0.7 | 0.7 | 1.3 | 1.3 | Â | Â |
NH4(0) | 648.4 | 445.5 | 191.3 | 847.5 | 238.2 | 466.2 | 265.5 |