Table 2 Practical identifiability analysis for the experimental scheme ES1 with (
) represents the nominal value for the parameters; δREFis the parameter mean value computed by the Monte-Carlo based approach; δREFis the relative distance between the mean and the nominal computed as 
, 
corresponds to the predicted maximum uncertainty of the given parameter and 
represents the uncertainty with respect to μREFin %.
) represents the nominal value for the parameters; δREFis the parameter mean value computed by the Monte-Carlo based approach; δREFis the relative distance between the mean and the nominal computed as 
, 
corresponds to the predicted maximum uncertainty of the given parameter and 
represents the uncertainty with respect to μREFin %.From: An iterative identification procedure for dynamic modeling of biochemical networks
Parameter | θ* | μ REF | δREF(in %) |
|
|
|---|---|---|---|---|---|
t 1 | 0.10 | 1.77 | 1680 | 1.79 | 100.7 |
t 2 | 0.10 | 6.16 | 6060 | 3.03 | 49.1 |
c 3a | 4.00 10-4 | 4.00 × 10-5 | 3.09 | 2.80 × 10-5 | 6.90 |
c 4a | 0.50 | 0.50 | 0.60 | 0.08 | 15.9 |
c 5 | 3.00 × 10-4 | 3.07 × 10-4 | 2.49 | 1.02 × 10-4 | 33.1 |
k 1 | 2.50 × 10-3 | 2.45 × 10-3 | 2.04 | 5.34 × 10-4 | 21.7 |
k 2 | 0.10 | 0.13 | 33.3 | 0.08 | 60.2 |
k 3 | 1.50 × 10-3 | 1.18 × 10-3 | 21.1 | 8.08 × 10-4 | 68.3 |
k prod | 2.50 × 10-5 | 3.25 × 10-5 | 29.9 | 3.19 × 10-5 | 98.3 |
k deg | 1.25 × 10-4 | 1.63 × 10-4 | 33.4 | 1.62 × 10-4 | 99.9 |
i 1 | 2.50 × 10-3 | 2.40 × 10-3 | 3.85 | 6.38 × 10-4 | 26.5 |
e 2a | 0.01 | 4.74 × 10-3 | 374 | 5.30 × 10-3 | 110.9 |
i 1a | 1.00 × 10-3 | 9.74 × 10-4 | 0.75 | 2.42 × 10-4 | 24.3 |