Table 1 Statistical analysis of iHSLN biological functions.
From: Human synthetic lethal inference as potential anti-cancer target gene detection
GO term - Biological function | P-value | % of genes in iHSLN | % of genes in GOA |
|---|---|---|---|
DNA replication | 5.20 E-28 | 6.8 | 40.9 |
DNA repair | 4.93 E-24 | 7.4 | 27.7 |
Response to DNA damage stimulus | 4.00 E-23 | 8.1 | 24.9 |
RNA processing | 4.56 E-15 | 8.7 | 17.9 |
Cell cycle | 2.50 E-13 | 9.8 | 15.7 |
Proteasomal protein catabolic process | 1.10 E-8 | 24.0 | 30 |
Golgi vesicle transport | 1.70 E-8 | 25.0 | 28.4 |