From: How to schedule VEGF and PD-1 inhibitors in combination cancer therapy?
Notation | Description |
---|---|
D | density of dendritic cells |
T 1 | density of activated CD 4+ T cells |
T 8 | density of activated CD 8+ T cells |
T r | density of activated Treg cells |
E | density of endothelial cells |
C | density of cancer cells |
N C | density of necrotic cell |
H | HMGB-1 concentration |
I 12 | IL-12 concentration |
I 2 | IL-2 concentration |
T β | TGF- β concentration |
W | oxygen concentration |
G | VEGF concentration |
P 1 | concentration of PD-1 on CD 4+ T cells |
P 8 | concentration of PD-1 on CD 8+ T cells |
L | PD-L1 concentration |
Q | PD-1-PD-L1 concentration |
A | anti-PD-L1 concentration |
B | anti-VEGF concentration |