Table 3 Initial conditions
From: Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus
Node | Initial value | Reason |
|---|---|---|
Apoptosis | False | We set apoptosis to False to see whether the input signals can cause apoptosis |
Caspases 3, 6, 7, 8, 9 | False | Caspases serve as the final mediators of apoptosis. So, we set them to False to see whether the input signals can activate them |