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Table 1 Initial condition for all simulations

From: In-silico comparison of two induction regimens (7 + 3 vs 7 + 3 plus additional bone marrow evaluation) in acute myeloid leukemia treatment

Compartment

Initial state

c1(t = 0)a

2 × 109 cells/kg

c2(t = 0)a

3.9 × 109 cells/kg

l1(t = 0)

1 cell/kg

l2(t = 0)

0 cells/kg

  1. aCompartment c1 and c2 start in the steady state of the healthy systems (without leukemic cells or therapy)