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Fig. 3 | BMC Systems Biology

Fig. 3

From: Constructing network topologies for multiple signal-encoding functions

Fig. 3

Bi-functional networks via module combinations. (a), (b) and (c) depict the results for one-node, two-node, and three-node merging, respectively. In each subfigure of (a), (b), (c), the upper left panel shows the form of node merging; two nodes in an ellipse represent the nodes that are merged, and the bottom left panel is the Q1,2 distribution of the combined bi-functional networks. Clustering analyses of the networks with relatively high Q1,2-values as marked by dashed red box in the histogram are depicted in the middle. The structure skeletons are illustrated on the right. d-f Examples of bi-functional combined networks that contain implicit interactions due to the competitive effect. Competitive edges are indicated in blue or purple. The dashed linkages represent the implicit interactions

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