From: Analysis of significant protein abundance from multiple reaction-monitoring data
Interaction scenario | True subject type | True run type | Sample size | Model | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LMM | LR-SAM | ||||||||||||
Best | (FF) | (FR) | (RF) | (RR) | L | W | W 1 | W S | S VC | ||||
IS1 | Fixed | Fixed | 20 | 0.296 | 0.301 | 0.459 | 0.077 | 0.044 | 0.417 | 0 | 0.01 | 0.042 | 0.258 |
50 | 0.627 | 0.63 | 0.85 | 0.333 | 0.216 | 0.798 | 0.548 | 0.14 | 0.291 | 0.756 | |||
100 | 0.916 | 0.917 | 0.994 | 0.709 | 0.632 | 0.996 | 0.984 | 0.424 | 0.694 | 0.995 | |||
Random | 20 | 0.302 | 0.303 | 0.39 | 0.085 | 0.093 | 0.42 | 0 | 0.007 | 0.034 | 0.253 | ||
50 | 0.642 | 0.646 | 0.715 | 0.321 | 0.336 | 0.805 | 0.534 | 0.154 | 0.288 | 0.775 | |||
100 | 0.921 | 0.923 | 0.958 | 0.681 | 0.753 | 0.99 | 0.981 | 0.405 | 0.668 | 0.99 | |||
Random | Fixed | 20 | 0.351 | 0.35 | 0.472 | 0.152 | 0.159 | 0.472 | 0.001 | 0.016 | 0.095 | 0.304 | |
50 | 0.626 | 0.628 | 0.782 | 0.384 | 0.403 | 0.825 | 0.574 | 0.218 | 0.359 | 0.782 | |||
100 | 0.85 | 0.851 | 0.928 | 0.659 | 0.705 | 0.985 | 0.976 | 0.457 | 0.652 | 0.983 | |||
Random | 20 | 0.379 | 0.381 | 0.43 | 0.176 | 0.186 | 0.488 | 0 | 0.024 | 0.106 | 0.348 | ||
50 | 0.613 | 0.615 | 0.674 | 0.366 | 0.389 | 0.812 | 0.552 | 0.19 | 0.342 | 0.775 | |||
100 | 0.834 | 0.835 | 0.873 | 0.655 | 0.679 | 0.989 | 0.981 | 0.447 | 0.639 | 0.98 | |||
IS2 | Fixed | Fixed | 20 | 0.328 | 0.331 | 0.482 | 0.083 | 0.039 | 0.662 | 0 | 0.005 | 0.042 | 0.503 |
50 | 0.619 | 0.62 | 0.865 | 0.298 | 0.199 | 0.978 | 0.87 | 0.095 | 0.268 | 0.966 | |||
100 | 0.889 | 0.889 | 0.996 | 0.696 | 0.621 | 1 | 1 | 0.279 | 0.676 | 1 | |||
Random | 20 | 0.288 | 0.29 | 0.382 | 0.067 | 0.074 | 0.649 | 0 | 0.006 | 0.023 | 0.466 | ||
50 | 0.648 | 0.652 | 0.735 | 0.339 | 0.363 | 0.979 | 0.888 | 0.112 | 0.305 | 0.97 | |||
100 | 0.921 | 0.921 | 0.96 | 0.703 | 0.748 | 1 | 1 | 0.288 | 0.685 | 1 | |||
Random | Fixed | 20 | 0.36 | 0.363 | 0.493 | 0.148 | 0.152 | 0.683 | 0.001 | 0.009 | 0.093 | 0.524 | |
50 | 0.599 | 0.602 | 0.76 | 0.363 | 0.377 | 0.982 | 0.878 | 0.137 | 0.334 | 0.961 | |||
100 | 0.861 | 0.861 | 0.93 | 0.674 | 0.715 | 1 | 1 | 0.321 | 0.66 | 1 | |||
Random | 20 | 0.384 | 0.386 | 0.462 | 0.175 | 0.191 | 0.682 | 0 | 0.007 | 0.113 | 0.523 | ||
50 | 0.583 | 0.586 | 0.637 | 0.357 | 0.384 | 0.968 | 0.869 | 0.123 | 0.323 | 0.952 | |||
100 | 0.836 | 0.836 | 0.874 | 0.655 | 0.698 | 1 | 1 | 0.33 | 0.644 | 1 |