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Fig. 1 | BMC Systems Biology

Fig. 1

From: NUP155 insufficiency recalibrates a pluripotent transcriptome with network remodeling of a cardiogenic signaling module

Fig. 1

Nucleoporins in cardiac differentiation. a Nup153, Nup155, Nup85, Rae1, and Tpr expression profiles during cardiac specification. Undifferentiated stem cells (ES LIF+); early differentiated stem cells (ES LIF-); cardiac precursors (CP), cardiomyocytes (CM). b ExAC constraint metrics and pLI values for Nup153, Nup155, Nup85, Rae1, and Tpr. c Venn diagrams intersect discrete gene groups independently parsed from the same high throughput dataset to identify nucleoporins (nup) that emerge as robust candidates involved in cardiogenesis. Nup155 is the highest priority molecule (p < 0.001). SOM = self-organizing map; QC = quality control

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BMC Systems Biology

ISSN: 1752-0509

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