SPSNet: subpopulation-sensitive network-based analysis of heterogeneous gene expression data

BMC Systems Biology

Table 3 Jaccard coefficients showing agreement between significant subnetworks obtained by PFSNet and SPSNet on training and test data

	Training	Test	Training ∩ test	Training ∪ test	Jaccard coefficient
PFSNet	27	24	11	40	0.28
SPSNet	87	77	62	102	0.61

Subnetworks reported significantly differentially expressed by SPSNet in the heterogeneous ALL phenotype are more reproducible (jaccard coefficients marked in bold) than PFSNet across training and test data

ISSN: 1752-0509