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Fig. 4 | BMC Systems Biology

Fig. 4

From: A homologous mapping method for three-dimensional reconstruction of protein networks reveals disease-associated mutations

Fig. 4

Our identified contacting and non-contacting residues association with binding affinity. a The average ddGs of contacting and non-contacting residues are 1.27 and 0.82 (p-value = 8.51E-05 by U-test), respectively. b The ratios of contacting and non-contacting residues are 0.56 (116/208) and 0.44 (92/208) in ddG > 1.5, respectively, and 0.38 (220/578) and 0.62 (358/578) in ddG < 1.5. The contacting residues are significantly enriched in ddG > 1.5 (p-value = 3.95E-06 by Fisher’s exact test)

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BMC Systems Biology

ISSN: 1752-0509

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