Fig. 3From: A homologous mapping method for three-dimensional reconstruction of protein networks reveals disease-associated mutationsThe enrichment (odds ratio) of our predicted interacting domains and contacting residues by using 5843 mutations recorded in OMIM. a The odds ratios of in-frame mutations in interacting domains (SCOP with blue and Pfam with red), contacting residues (green), non-interacting domains (SCOP with dot blue and Pfam with dot red), and non-contacting residues (dot green). b The odds ratios of in-frame mutations are colored according to their types: contacting residues for forming hydrogen-bond (blue), conserved (red), and for forming hydrogen-bond and conserved (green); other residues for forming hydrogen-bond (dot blue), conserved (dot red), and for forming hydrogen-bond and conserved (dot green). The odds ratios of in-frame mutations are significantly enriched in the interacting domains and contacting residuesBack to article page