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Table 1 Functional scores of gene lists derived from Informed Walks and network centrality measures

From: Informed walks: whispering hints to gene hunters inside networks’ jungle

 

Prioritization based on Informed Walks

Prioritization based on Degree centrality

Prioritization based on Betweenness centrality

Prioritization based on Closeness centrality

Average of Functional Similarity Score

Number of significant genes

Average of Functional Similarity Score

Number of significant genes

Average of Functional Similarity Score

Number of significant genes

Average of Functional Similarity Score

Number of significant genes

Breast

0.968

186

0.949

92

0.947

97

0.941

100

Colon

0.771

179

0.682

84

0.683

76

0.673

80

Colorectal

0.983

153

0.939

63

0.948

56

0.957

56

Rectum

0.566

41

0.381

8

0.402

12

0.392

15

Ovarian

0.914

252

0.873

131

0.873

112

0.866

116

Glioma

0.875

284

0.861

75

0.829

102

0.823

106

Glioblastoma

0.905

287

0.873

118

0.870

113

0.869

100