Fig. 6

Prediction of bortezomib sensitivity in multiple myeloma patients. Strip charts and boxplots in (a), (b), and (c) show predicted drug sensitivity for in vivo responders and non-responders to bortezomib using A2 + RR, A1 + RR and B + RR prediction algorithms, respectively. Strip charts and boxplots (d), (e), and (f) further break down responders and non-responders of strip charts and boxplots (a, (b,) and (c) as showing CR, PR, MR, NC or PD using A2 + RR, A1 + RR and B + RR, respectively, prediction algorithms. (g) ROC curves illustrating estimated prediction accuracy of prediction algorithms. CR, complete response; PR, partial response; MR, minimal response; NC, no change; PD, progressive disease