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Fig. 1 | BMC Systems Biology

Fig. 1

From: The CD4+ T cell regulatory network mediates inflammatory responses during acute hyperinsulinemia: a simulation study

Fig. 1

Experimental design of simulations. a The network and regulatory functions were grounded on published experimental results. b The different inflammatory conditions were simulated by fixing the values of the input nodes of the network that represent the extrinsic cytokines present in the microenvironment. For each simulated condition, the attractors and basins of attraction of the network were obtained. c The attractors of the network were perturbed by fixing the value of the target node for one time step and then returning the node to its original function or value; the system attractor was determined

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