Fig. 6
From: Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching
Total PSMAD time-course for a certain TGF-β concentration. Total PSMAD time-course for a certain TGF-β concentration. Simulation results for low membrane receptor concentration condition (or so called early-stage tumors) are compared with the simulation results for high membrane receptor concentration condition (or so called late-stage tumors). These conditions were simulated via altering the receptor production rate on the membrane. Note that the units of PSMAD concentration levels are arbitrary