From: Predicting network modules of cell cycle regulators using relative protein abundance statistics
Eliminated reaction | Single mutation strains that are viable before and |
---|---|
(rate constant) | inviable after setting the rate constant to zero |
Whi5 phosphorylation by Bck2 (k p i5k2) | cln3 Δ, Multicopy BCK2, cdh1 Δ, sic1 Δ, swi5 Δ, |
CLB5-db Δ, net1-ts, GAL-CLB2, APC-A | |
CKI phosphorylation by Cln2 (e k i,n2) | bck2 Δ, GAL-SIC1, net1-ts, APC-A |
CKI phosphorylation by Clb2 (e k i,b2) | GAL-CLN3, cdh1 Δ, GAL-CLB5, CLB1 clb2 Δ |
CKI dephosphorylation by Cdc14 (k d p k i,14) | bck2 Δ, cdh1 Δ, GAL-CLB2, APC-A |
Whi5 phosphorylation by Cln3 (k p i5n3) | bck2 Δ, cdh1 Δ, APC-A |
SBF phosphorylation by Clb2 (k p b f b2) | cdh1 Δ, CLB5-db Δ, APC-A |
Whi5 phosphorylation by Cln2 (k p i5n2) | bck2 Δ, APC-A |
Whi5 dephosphorylation by Cdc14 (k d p i514) | APC-A |
Net1 dephosphorylation by PPX (k d p n e t,p x ) | Multicopy CDC15 |