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Fig. 6 | BMC Systems Biology

Fig. 6

From: Rewiring of the inferred protein interactome during blood development studied with the tool PPICompare

Fig. 6

Distributions of alteration types for the minimum amount of explanatory reasons for rewiring events. Shown is the contribution of the two elementary types of conceivable protein alterations in PPICompare, DE and AS, to the solutions of the optimization regarding the small sets of likely changes that explain all rewiring. The contributions are normalized by their direction (left plot) or by their proportion in individual transitions (right plot). In the left plot, “+” (blue) means emerging interactions and “-” (green) means vanishing interactions

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