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Fig. 6 | BMC Systems Biology

Fig. 6

From: A combined model reduction algorithm for controlled biochemical systems

Fig. 6

Timecourses of the output from the original 99-dimensional and the reduced 8-dimensional systems. This plot emphasises the fact that the reduced model is designed to remain valid for any reasonable change in input. The system starts by being affected by an agonist that increases the rate of EGF binding by 25% for 50 minutes, at this point the input flips to an antagonist decreasing the rate of EGF binding by 50% and runs for the same time period. At any given time point the error between the original and reduced model exceeds no more than 5%

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