From: Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency
Gene symbol | Gene name | Fold Change HFE/LFE | Gene function |
---|---|---|---|
MB | Myoglobin | 4.10 Down | Iron storage, highly expressed in red, slow fibres |
MYH15 | Myosin heavy chain 15, slow | 4.46 Down | Slow twitch fibre isoform |
TPM3 | Tropomyosin 3, slow | 2.67 Down | Slow twitch fibre isoform |
MYOZ2 | Myozenin 2, slow | 2.54 Down | Slow twitch fibre isoform |
TNNI1 | Troponin I type I, slow | 3.36 Down | Slow twitch fibre isoform |
PLN | Phospholamban | 2.78 Down | Highly expressed in slow twitch fibres, substrate for cAMP-dependent protein kinase. |
COL3A1 | Collagen 3A1 | 2.09 Down | ECM |
COL12A1 | Collagen 12A1 | 2.66 Down | ECM |
FN1 | Fibronectin 1 | 2.01 Down | ECM |
BMP5 | Bone morphogenetic protein 5 | 4.23 Down | Negative regulation of IGF1 signaling |
RSFR | Leukocyte ribonuclease A2 | 2.56 Down | Angiogenesis |
LY86 | Lymphocyte antigen 86 | 2.42 Down | Inflammation, apoptosis |
MGAT5B | beta-1,6-N-acetylglucosaminyltransferase | 3.51 Down | Synthesis of cell surface n-glycans, ECM |
NES | Nestin | 2.64 Down | Expressed in nerve cells, implies motor unit |
APOA1 | Apolipoprotein A1 | 2.27 Down | Promotes cholesterol efflux from tissues. Highly expressed in liver. |
MGP | Matrix Gla protein | 1.84 Down | ECM |
IGJ | Immunoglobulin J polypeptide | 2.21 Down | Little known |
SEPP1 | Selenoprotein P | 2.19 Down | Extracellular glycoprotein and antioxidant |
CA3 | Carbonic anhydrase III | 1.93 Down | Response to oxidative stress, expressed at high levels in skeletal muscle |
CTSS | Cathepsin S | 2.24 Down | Lysosomal cysteine proteinase |
H2AFY | Histone family member Y | 2.47 Up | Associated with lipogenic genes |
HIG2A (ENSGALG00000003348) | Hypoxia-inducible domain family | 2.15 Up | Little known |
TESK1 | Testis specific kinase | 1.95 Up | Cell matrix communication |
C11ORF89 * | Uannotated ORF | 2.44 Up | Unannotated |
CKMT1 | Creatine kinase mitochondrial 1 | 1.63 Up | Creatine metabolism, muscle energy supply |
CNTFR | Ciliary Neurotrophic factor | 2.20 Up | Skeletal muscle development |
ENKD1 | Enkurin domain containing | 2.19 Up | Cytoplasmic microtubule protein |
CA4 | Carbonic anhydrase 4 | 3.95 Up | Respiration, acid base balance, expressed on luminal surface of capillaries |
INSIG1 | Insulin induced gene 1 | 1.92 Up | Regulation of intracellular cholesterol concentration and steroid biosynthesis |
TTPA | Tocopherol (alpha) binding protein | 2.84 Up | Binds alpha-tocopherol a form of vitamin E, response to pH |
LINGO1 | Leucine rich repeat and Ig domain containing 1 | 1.72 Up | Nervous system development |
DCUN1D5 | Defective in cullin neddylation 1, domain containing 5 | 2.10 Up | Ubiquitin conjugating enzyme binding |
SNCG1 | Synuclein gamma | 3.40 Up | Synapse protein |
C16ORF45 | Unannotated ORF | 1.88 Up | Protein function unknown |
LIPG | Endothelial lipase | 2.20 Up | Lipoprotein metabolism and vascular biology |
(ENSGALG00000028983) | BLASTS to HOXA9 | 2.33 Up | Transcription Factor |
(ENSGALG00000027955) | BLASTS to MHC | 2.31 Up | MHC immune function |
BFSP1 | Beaded filament structural protein 1 | 3.16 Up | Cytoskeletal structure |
MYL2_1 (MYL2A) | MYL2A | 3.39 Up | Thought to be more highly expressed in cardiac muscle i.e. slow fibres |
MYBPH | Myosin binding protein H | 1.53 Up | Fast isoform |