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Fig. 1 | BMC Systems Biology

Fig. 1

From: Gene regulatory network underlying the immortalization of epithelial cells

Fig. 1

Gene Regulatory Network underlying spontaneous immortalization. a Gene regulatory network for epithelial carcinogenesis. b A Core Regulatory Network Module Underlying Spontaneous Immortalization and Epithelial–Mesenchymal Transition. c Predicted gene expression profiles characterizing the epithelial, senescent and mesenchymal stem–like cells. d Cellular inflammation increases the size of the basin of attraction of the mesenchymal stem–like phenotype

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