Fig. 3From: Combining laboratory and mathematical models to infer mechanisms underlying kinetic changes in macrophage susceptibility to an RNA virusSusceptibility and CD163 dynamics. Batch specific least square mean (LSM) percentages and standard errors obtained from the experimental data (a–c) and from the predictions of model B (d–f) obtained by linear mixed model analysis. Batches 1 and 3 consisted of three biological replicates (i.e. cells from three different pigs), and batch 2 comprised two biological replicates. The estimates refer to the proportion of PAMs classified as infected (a & d), CD163 positive (b & e), and CD163 positive within the set of infected cells (c & f), after incubation for 0, 1, 2, 4, 6, 8 and 9 days, respectively, before PRRSV (infected) or mock-infection (control). Estimates refer to 18 h post (mock) infection. Predictions refer to refined model B with assumption AS1 (i.e. switching rates independent of CD163, σ1,max = σ2,max = σmax)Back to article page