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Fig. 2 | BMC Systems Biology

Fig. 2

From: A novel integrated gene coexpression analysis approach reveals a prognostic three-transcription-factor signature for glioma molecular subtypes

Fig. 2

The clustering heat maps and survival analysis results with three-TF signature in five data sets. The numbers of clusters (k) were determined by NMF based on the expression signatures of 3 TFs. Heat maps of three-TF DRA signature in glioma samples are shown on the left. a-e are respectively GSE16011, Rembrandt, Tiantan, TCGA mRNA-seq and GSE4412 data sets. Kaplan-Meier survival curves of the overall survival for the patients from each molecular subtype are shown on the right. P-values of the survival curves were calculated by using log-rank tests. The same colour codes were used in the heat maps and the Kaplan-Meier survival curves of all datasets. The three colours green, red, yellow refer respectively to ZG, NG and IG subtypes

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