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Table 4 Commonly enriched gene sets of doxorubicin and H-7 in the DREAM dataset

From: A simple gene set-based method accurately predicts the synergy of drug pairs

Gene set

MSigDB category

NEWMAN_ERCC6_TARGETS_DN

Chemical and genetic perturbations

LEE_NEURAL_CREST_STEM_CELL_DN

Chemical and genetic perturbations

ODONNELL_METASTASIS_UP

Chemical and genetic perturbations

CERVERA_SDHB_TARGETS_2

Chemical and genetic perturbations

OSADA_ASCL1_TARGETS_UP

Chemical and genetic perturbations

YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP

Chemical and genetic perturbations

HINATA_NFKB_TARGETS_KERATINOCYTE_DN

Chemical and genetic perturbations

TAVAZOIE_METASTASIS

Chemical and genetic perturbations

VALK_AML_CLUSTER_7

Chemical and genetic perturbations

MIKKELSEN_NPC_ICP_WITH_H3K27ME3

Chemical and genetic perturbations

HOELZEL_NF1_TARGETS_UP

Chemical and genetic perturbations

PTEN_DN.V2_UP

Oncogenic signatures

KRAS.DF.V1_DN

Oncogenic signatures

Response to wounding

Gene ontology terms