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Fig. 3 | BMC Systems Biology

Fig. 3

From: Metabolic host responses to malarial infection during the intraerythrocytic developmental cycle

Fig. 3

Predicted time-dependent production of biomass metabolites for the HB3, 3D7, and Dd2 strains of Plasmodium falciparum. The heat map denotes the predicted time-dependent production levels of each biomass metabolite of P. falciparum, in which orange, grey, and blue colors represent high, normal, and low production levels, respectively. Based on the time-dependent production, we classified these metabolites into four groups. Groups I, II, and III include the metabolites mainly produced during the early (ring stage), middle (trophozoite and early schizont stages), and late (schizont stage) periods of the intraerythrocytic developmental cycle, respectively, whereas group IV includes the metabolites for which the production levels were basically constant throughout the intraerythrocytic developmental cycle. Production value of each individual metabolite is normalized with respect to the median of its value for the HB3 strain

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