Low potency toxins reveal dense interaction networks in metabolism

BMC Systems Biology

Table 2 Correlation of Ub with other biological endpoints

Endpoint	Number	UB₅	Ub₆
HERG	229	−0.062	0.179**
Oestrogenic	131	−0.024	−0.342***
Tadpole narcosis	141	−0.043	−0.267**
COX-2	107	−0.069	−0.149
Antihistamine	61	−0.097	−0.0126

Rank correlation coefficient of three target-related toxicity measures and two pharmacological endpoints with UnBiological measures Ub ₅ and Ub ₆. Column 1: Pharmacological endpoint. Column 2: number of data points. Columns 3 and 4: correlations with Ub ₅ and Ub ₆ respectively. Significance flags are the same as in Table 1

ISSN: 1752-0509