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Fig. 5 | BMC Systems Biology

Fig. 5

From: Feedback control in planarian stem cell systems

Fig. 5

The temporal pattern of size, total mortality of differentiated cells, total mortality of differentiated cells, and fraction of neoblasts under growth, degrowth, and regrowth for a situation in which the planarian starts in an environment with Y e =450 at 20 % of its steady state size. For simplicity of presentation, we scale time and divide all times in the model by 10,000 for presentation in figures. At scaled time t= 7 food is dropped to Y e =400 and then at scaled time t=14 increased to Y e =480. Even in the absence of a resource constraint, the cell population dynamics show a dependence upon the level of food in the environment. This is due to the feedback control on the activity of neoblasts

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