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Table 1 Performance of the five approaches

From: Inference of domain-disease associations from domain-protein, protein-disease and disease-disease relationships

Approach

AUC

Accuracy

Mean rank ratio

Association

0.7900

0.6256

0.2432

MLE

0.8407

0.7074

0.1914

DPEA

0.8309

0.6513

0.2177

Bayesian

0.8554

0.7289

0.1872

PE

0.8262

0.6525

0.2282

  1. The AUC, accuracy and mean rank ratio of the Association, MLE (fp = 0, fn = 0.9), DPEA, Bayesian (u p , u n  = 0, v p , v n  = 1, and α = 2, β = 2), and PE (r = 100 %, and pw threshold ≤ 0.01) approaches for predicting domain-disease associations, respectively
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BMC Systems Biology

ISSN: 1752-0509

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