Skip to main content

Table 2 The distribution of top 20 functional domains for human E3 ligases

From: A new scheme to discover functional associations and regulatory networks of E3 ubiquitin ligases

No.

InterPro ID

Domain terms

Number of proteins

% Total

1

IPR001680

WD40 repeat

287

57.5150 %

2

IPR006652

Kelch repeat type 1

68

13.6273 %

3

IPR000408

Regulator of chromosome condensation, RCC1

55

11.0220 %

4

IPR001841

Zinc finger, RING-type

54

10.8216 %

5

IPR000315

Zinc finger, B-box

48

9.6192 %

6

IPR003877

SPla/RYanodine receptor SPRY

38

7.6152 %

7

IPR013069

BTB/POZ

28

5.6112 %

8

IPR000569

HECT

28

5.6112 %

9

IPR001202

WW/Rsp5/WWP

28

5.6112 %

10

IPR020683

Ankyrin repeat-containing domain

27

5.4108 %

11

IPR001496

SOCS protein, C-terminal

25

5.0100 %

12

IPR002867

Zinc finger, C6HC-type

23

4.6092 %

13

IPR018957

Zinc finger, C3HC4 RING-type

22

4.4088 %

14

IPR001258

NHL repeat

21

4.2084 %

15

IPR011705

BTB/Kelch-associated

15

3.0060 %

16

IPR002110

Ankyrin repeat

14

2.8056 %

17

IPR000571

Zinc finger, CCCH-type

11

2.2044 %

18

IPR001876

Zinc finger, RanBP2-type

11

2.2044 %

19

IPR011016

Zinc finger, RING-CH-type

11

2.2044 %

20

IPR001452

Src homology-3 domain

10

2.0040 %