Fig. 3

c-Myc cooperates with Kaposin B to regulate cellular novel miRNAs. a The analysis pipeline for identification of known and novel miRNAs from smRNA-seq data. Reads or sequences pass each filtration process are indicated. b Venn diagrams summarizing significant overlap between c-Myc and Kaposin B signature novel miRNAs. (upper panel) up-regulated miRNAs; (lower panel) down-regulated miRNAs. c Venn diagrams summarizing significant overlap between up-regulated or down-regulated novel miRNA candidates and Ago1/2(+) RNA-IP-seq data. d Detailed information of 5 c-Myc-promoting and -reducing novel miRNAs that expressed higher reads in different groups. e Deduced RNA secondary structures of a set of newly discovered miRNAs