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Fig. 4 | BMC Systems Biology

Fig. 4

From: Tracing regulatory routes in metabolism using generalised supply-demand analysis

Fig. 4

Rate characteristic plots of the reaction blocks of Ï• A in the pyruvate branch model. a The fluxes of the demand block 12, and the supply blocks 1 and 5 of Ï• A . The unlabelled dashed curve represents the total supply. b The rate characteristic plot of the Ï• A -supply block 5 with partial and total response coefficients indicated as lines intersecting the J 5-curve at the steady-state value of Ï• A . Partial response coefficients (solid lines) indicate the relative contribution of each route of interaction of Ï• A with block 5 towards the total response coefficient (dashed line). The steady-state value of Ï• A is indicated as a vertical dotted line in both (a) and (b) (see Table 1)

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