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Table 1 Growth kinetics, carbon source consumption and product formation rate in batch cultivations and FBA simulation. The numbers represent mean values and deviations from the mean of triplicate cultivations

From: Optimization of lipid production with a genome-scale model of Yarrowia lipolytica

 

Glucose

Glycerol

 

Experiment

Simulation

Experiment

Simulation

μmax (h−1)

0.33 ± 0.02

0.339

0.45 ± 0.01

0.442

YSX (g g−1)

0.46 ± 0.04

0.520

0.55 ± 0.02

0.559

rS (mmol gDW −1 h−1)

4.00 ± 0.35

4.00

8.78 ± 0.20

8.78

rcit (mmol gDW −1 h−1)

n.d.

0

n.d.

0

  1. YSX: biomass yield, rS: specific uptake rates glucose or glycerol; rCit: citrate excretion rate, μmax: specific growth rate, n.d. : not detected