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Table 1 Primary findings from the analyses using signaling pathways from Reactome, KEGG and WikiPathway in breast cancer cell-line: SKBR3 (GSE38376)

From: Prediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling

Pathway

# of signaling

Pathway of

All

Distinct

All putative

Distinct

# of other

source

pathways

interest

Cross-talks

gene-pairs §

drug-resistant

gene-pairs ¶

signaling

of interest

cross-talks

pathways

REACTOME

23

EGFR

1,083

841

104

97

13

KEGG

35

ErbB

2,179

1,050

188

99

26

WikiPathway

63

ErbB

3,084

876

299

96

51

  1. ¶Number of distinct gene-pairs involved in all EGFR/ErbB cross-talks with all other signaling pathways; §Number of distinct gene-pairs commonly involved in all EGFR/ErbB cross-talks and drug resistance.