Identification of network-based biomarkers of cardioembolic stroke using a systems biology approach with time series data

Table 3 Functional analyses of the network biomarker at 3 h post- stroke.

Name	pvalue	Ratio
Top canonical pathways
GABA receptor signaling	1.66E-02	1/67
Renal cell carcinoma signaling	1.75E-02	1/71
Toll-like receptor signaling	1.83E-02	1/74
Hereditary breast cancer signaling	2.83E-02	1/115
RhoA signaling	3.00E-02	1/122
Top disease and biological functions
Cardiovascular disease	2.49E-04 ~ 3.94E-02
Developmental disorder	2.49E-04 ~ 3.94E-02
Hereditary disorder	2.49E-04 ~ 1.24E-03
Organismal injury and abnormalities	2.49E-04 ~ 3.94E-02
Skeletal and muscular disorders	2.49E-04 ~ 3.94E-02
Physiological system development and function
Embryonic development	6.94E-05 ~ 4.35E-02
Organismal development	9.92E-05 ~ 4.35E-02
Cardiovascular system development and function	4.98E-04 ~ 3.85E-02
Hematological system development and function	4.98E-04 ~ 1.48E-02
Hepatic system development and function	4.98E-04 ~ 3.00E-02

ISSN: 1752-0509