From: Relative impact of multi-layered genomic data on gene expression phenotypes in serous ovarian tumors
Genomic feature | Type | N | Most significant GO term | p-value (FDR) | Most significant SP-PIR keyword | p-value (FDR) |
---|---|---|---|---|---|---|
hsa.miR.768.5p | miRNA | 303 | GO:0005739 mitochondrion | 8.67E-09 (1.18E-05) | acetylation | 1.10E-22 (1.40E-19) |
hsa.miR.29a | miRNA | 154 | GO:0007049 cell cycle | 7.99E-20 (1.21E-16) | cell cycle | 7.30E-17 (1.44E-13) |
SPRY4 | methylation | 119 | GO:0003723 RNA binding | 3.19E-4 (0.4197) | acetylation | 1.09E-6 (0.0013) |
16p13.3 | CNA | 117 | GO:0031974 membrane-enclosed lumen | 4.10E-5 (0.0506) | iron-sulfur | 9.98E-5 (0.1257) |
12q23.1 | CNA | 113 | GO:0070013 intracellular organelle lumen | 4.29E-5 (0.0534) | acetylation | 2.62E-6 (0.0032) |
1q42.3 | CNA | 113 | GO:0012505 endomembrane system | 7.3E-4 (0.8908) | phosphoprotein | 4.71E-6 (0.0059) |
6p21.1 | CNA | 109 | GO:0042974 retinoic acid receptor binding | 4.86E-8 (6.38E-5) | nucleus | 1.84E-5 (0.0228) |
17q25.3 | CNA | 108 | non-membrane-bounded organelle | 0.0092 (11.23) | acetylation | 6.39E-9 (8.03E-6) |
1p36.11 | CNA | 103 | GO:0016071 mRNA metabolic process | 0.0046 (6.86) | phosphoprotein | 1.31E-4 (0.1632) |
19p13.12 | CNA | 102 | GO:0043232 intracellular non-membrane-bounded organelle | 1.24E-5 (0.0150) | nucleus | 1.24E-5 (0.0149) |