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Table 7 Protein domain property analysis result.

From: Stringent DDI-based Prediction of H. sapiens-M. tuberculosis H37Rv Protein-Protein Interactions

Organism

H. sapiens proteins

H. sapiens proteins

PPIN

Hum-Mtb

Hum-Hum

Hum-HIV

Hum-Hum

Average No. of domains

1.79

1.31

1.42

1.27

P-value

4.40E-5

9.14E-17

Average Domain degrees

17.95

10.22

13.23

9.21

P-value

1.79E-2

1.04E-10

  1. This table summarizes the protein domain analysis for H. sapiens proteins involved in the host-pathogen PPI dataset predicted by our stringent DDI-based approach comparing with the proteins involved in intra-species PPIN. Protein domain property analysis for H. sapiens proteins involved in gold standard H. sapiens-HIV PPI dataset [19] has also been conducted. In the table there are some abbreviations. Hum-Mtb: in predicted H. sapiens-M. tuberculosis H37Rv PPIN. Hum-Hum: in H. sapiens intra-species PPIN. Hum-HIV: in gold standard H. sapiens-HIV PPIN.